Research Senior Associate

The Research Senior Associate will support and manage translational cancer immunotherapy research projects focused on antibody engineering and antibody-based cell therapy platforms. This role involves contributing to the design, execution, and analysis of experiments; supporting project planning; and coordinating daily research operations related to the development and evaluation of antibody therapeutics, including antibody drug conjugates (ADCs), bispecifics, and CAR-NK/CAR-T cells.

Key Responsibilities:

• Independently plans and conducts laboratory experiments involving complex in vitro and in vivo techniques.
• Executes molecular biology protocols (e.g., DNA/RNA extraction, RT-PCR), antibody and protein production, purification, and characterization.
• Performs immunological and biochemical assays (e.g., flow cytometry, ELISA, Western blotting, SDS-PAGE, Biacore/SPR, IncuCyte or RTCA cytotoxicity assays, ADCC/CDC assays).
• Supports small animal studies, including injections (tail vein, intraperitoneal, subcutaneous), tumor modeling, and in vivo imaging.
• Analyzes experimental data, prepares figures and reports, and maintains accurate laboratory records.
• Assists with the development of grant proposals and manuscripts in collaboration with principal investigators.
• Oversees technical staff and provides training in relevant techniques and protocols.
• Maintains laboratory equipment and inventory; ensures compliance with institutional, state, and federal safety regulations (including OSHA).
• Coordinates usage and maintenance of shared instrumentation within the PIIO Center for Antibody Therapeutics.

Qualifications
Master's Degree in Biochemistry, Molecular Biology or other biological/health science degree or equivalent experience required; 3 years of relevant experience required with Bachelor's Degree, or 1 year of relevant experience required with Master's Degree

Interested candidates should submit a cover letter, resume, and contact information for three professional references through the Ohio State University job portal.

The Ohio State University is a dynamic community of diverse resources, where opportunity thrives and where individuals transform themselves and the world. The Ohio State University is one of the nations largest and most comprehensive public universities and a top employer in Ohio.

As one of only 57 designated comprehensive cancer centers in the nation, The Ohio State University Comprehensive Cancer Center Arthur G. James Cancer Hospital and Richard J. Solove Research Institute is dedicated to the creation of knowledge in laboratory, clinical and population-based cancer research. We apply those discoveries to develop more effective approaches to cancer prevention, diagnosis, and therapies providing tomorrows standard of care today. A Cancer-Free World Begins Here.

The OSUCCC James is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nations largest public universities. is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nations largest public universities.