Biomarker Principal Scientist II (LAB-BASED)

Job Description Summary

Job Description

Key Responsibilities:

• Demonstrate creativity and resourcefulness in identifying, conducting evaluation and implementing new cutting-edge technologies to fill biomarker needs and gaps
• Provide Subject matter expertise in soluble biomarker area (e.g., ligand binding assay, mass spectrometry,...) with knowledge in other biomarker modalities and technologies (e.g., flow cytometry, PCR, Next Generation Sequencing,...)
• Develop, validate and implement targeted singleplex / multiplex biomarker assays internally by working in labs and/or at external vendors via scientific monitoring.
• Execute biomarker plan and successfully implement biomarker activities (internally and/or at external vendors) to support clinical studies. Ensure quality and timely delivery of data
• Generate and interpret data to enable proof of mechanism, inform dose selection & proof of biology in clinical programs and present results at internal meetings
• Translate literature and mechanistic hypotheses into experimental designs that support the biomarker context of use
• Provide scientific oversight for internal and external collaborations including study design, QC strategy, and data interpretation.
• Publish and present findings at internal and external scientific forums.

Essential Requirements:

• MS in Biology, biochemistry or related discipline required.
• 12 years of in scientific and technical discipline of biomarker method development and validation in CROs or industry.
• Emerging technology leader who is passionate about driving patient-centric innovation by leveraging cutting-edge technologies
• Proficiency running variety of immunoassay platforms (such as MSD, Luminex, Ella,Quanterix Simoa), Mass Spectrometry, automated Western blots, Cobas is a plus. Experience with multiplex assays and profiling platforms is highly desired
• Experience in troubleshooting of assays and assay transfer to CROs
• Experience working in a global organization and matrix-resourcing model with good computer skills (Excel, Word, PowerPoint, SoftMaxPro, SMART Book, Spotfire, GraphPad Prism, Watson LIMS).
• Illustrated ability to be creative, self-motivated, willingness to accept responsibility, work collaboratively and independently.
• Excellent oral and written communication skills

The salary for this position is expected to range between $114,100 and $211,900 per year.

The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.

EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.

Accessibility and reasonable accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to us.reasonableaccommodations@novartis.com or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Salary Range

Skills Desired