Senior Director, Supply Chain Digital Strategy

The Senior Director, Supply Chain Digital Strategy will be a key business leader responsible for shaping and delivering the digital transformation vision for Alnylam's supply chain. This role will own the digital supply chain product vision and roadmap, ensuring that investments in data, systems, and processes deliver measurable business value across Clinical and Commercial Supply, Global Planning, and Logistics.

Anchored in supply chain but collaborating across Technical Operations & Quality (TOQ) - including CMC, Manufacturing, Quality, and Facilities - this leader will align digital priorities across functions, enable seamless data integration, and standardize core business processes. Acting as the business counterpart to IT, they will define enterprise process and data standards, prioritize initiatives, and drive adoption strategies that ensure technology solutions are scalable, connected, and future-ready.

This is a hybrid position based primarily at Alnylam's Cambridge, MA office. The individual in this role will be expected to work on-site at least two days per week. At this time, we are not considering remote candidates.

Key Responsibilities

• Serve as the business owner for supply chain digital products, ensuring a clear, cohesive product vision aligned with enterprise strategy.
• Develop and maintain a multi-year digital roadmap that balances innovation with operational readiness.
• Prioritize digital initiatives based on business value, feasibility, and strategic fit.

• Define and implement robust business-side data governance structures across supply chain domains.
• Establish clear data ownership and stewardship roles in partnership with IT, ensuring process accountability and alignment with enterprise governance standards.
• Ensure data integrity, harmonization, and lifecycle management across planning, inventory, distribution, and manufacturing master data.

• Partner with IT to drive seamless interoperability across core systems, including ERP, CTMS, MES, LIMS, and planning platforms.

• Ensure end-to-end integration between Clinical and Commercial Supply systems, enabling visibility and data flow across the product lifecycle.
• Support integration of Clinical Supply systems including IRT, CTMS, and clinical forecasting tools with enterprise systems to enable protocol demand visibility, country-specific supply planning, and inventory tracking.

• Develop and execute change management and adoption strategies to ensure new capabilities are fully utilized.
• Measure and communicate realized business value from digital investments.

• Lead the design of scalable digital engagement models with CMOs, suppliers, and 3PLs to enable visibility, traceability, and real-time data exchange.
• Define business process expectations and data standards for external integration platforms.

• Establish and govern enterprise supply chain KPIs and digital performance metrics.
• Enable self-service data access and operational dashboards for decision-making.

• Build foundational data/process infrastructure for AI, predictive analytics, and machine learning.
• Partner with analytics teams to pilot and scale advanced capabilities.

• Champion a culture of digital fluency and data-driven decision-making.
• Lead cross-functional training, engagement, and continuous improvement initiatives.

Qualifications

• Bachelor's or Master's degree in Supply Chain, Information Systems, Engineering, or a related field.

• 15+ years in supply chain, operations, or digital transformation in life sciences.
• Proven track record leading enterprise digital strategy and product vision execution.
• Deep expertise in systems integration, data governance, and business process architecture.
• Experience implementing major platforms across ERP, APS, MES, LIMS, WMS domains.
• Strong cross-functional leadership and change management skills.

• Strategic thinker with a systems mindset and ability to connect data, process, and platform design.
• Collaborative leader who can influence across business, IT, and external partners.
• Strong understanding of supply chain operating models, KPIs, and external collaboration frameworks.
• Experience with data governance frameworks and enterprise-level change management.

About Alnylam:Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by "interfering" with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality.

Our culture:Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we've been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2023 for the third consecutive year, one of Science Magazine's Top Biopharma Employers, one of America's Most Responsible Companies for 2024 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK - among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients. Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law.