Our lab focuses on mechanisms of T-cell dysfunction in the context of central nervous system tumors, including T-cell exhaustion and sequestration. This strong immunologic foundation serves as the basis for our active development of cell and biologic therapeutics, including chimeric antigen receptor (CAR) T-cells and T-cell and antigen bispecifics (TCABs). We are further currently modeling cutting-edge neurosurgical therapies ("bedside to bench") alongside colleagues in biomedical engineering and veterinary medicine. Our team is comprised of a unique mix of scientists, clinicians, and students working to improve the care of patients with brain tumors. |
Key Responsibilities: * Services - PhD Candidate Researcher o Contribute to research & operations of the lab o Plan/run experiments o Write/review/contribute to Fecci Lab scientific papers o Collaborate with other lab members o Maintain and improve lab environment - tidy & friendly o Present research at conferences/retreats o Mentor other lab members o Complete coursework/obligations required by BME PhD Department * Deliverables (July 2025 - January 2026) o Successful completion of remaining Duke coursework requirements * 15 credits of coursework * 2 Teaching Assistant Experiences * 2 Teaching Assistant Seminars o Relocation to Denver, CO and completion of University of Colorado - Anschutz onboarding requirements o Progress on first author review paper o Submission of F31 application o Contributions to miscellaneous Fecci Lab tasks that can be completed virtually (i.e. writing and experimental planning) o Conducting research in the Fecci lab as a visiting scholar until the completion of her PhD - ideally by the Summer of 2029 o If needed, additional time to complete PhD will be discussed and arranged with Dr. Fecci, The University of Colorado, and Duke University. |