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Director, Market Access Transformation & Strategic Marketing

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
Sep 10, 2025

Job Description

Vertex currently operates at the forefront of rare disease scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), Sickle Cell Disease and Transfusion-Dependent Beta Thalassemia. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in Pain, Type 1 diabetes, IgA Nephropathy (IgAN), APOL-1 Mediated Kidney Disease, and Muscular Dystrophy, among others.

The Director, Market Access Transformation & Strategic Marketing is accountable for leading the development of a strategic "above-brand" market access platform to help guide portfolio investments and support customer engagement as well as access across the Vertex portfolio. This role will focus on three core areas:

Above brand initiatives that "connect the dots" within the Vertex portfolio along with the vertical integration of the large mega accounts (Payer & Trade); move from transactional relationships to professional alliances Customer and competitive insight mining to develop big innovative ideas which align and complement the transformative Vertex portfolio of products to bring the most value to patients (e.g., alternative contracting models, patient centric initiatives, health equity strategies and value frameworks) Elevate Market Access knowledge across the organization to ensure the latest Access trends are incorporated into product launch GTM strategies, pipeline, brand planning and long range planning initiatives

Additionally, this will include conducting annual market landscape scans, and ensuring a streamlined, one Vertex voice related to customer engagements (preapproval information exchanges, value prop development and supporting deliverables) to ensure optimal impact and utility. This is a highly visible, cross functional role that will work closely with matrixed teams across the MA portfolio to ensure strategic integration, advancing long term MA goals.

Key Duties and Responsibilities:

  • Own and integrate Above Brand/Unbranded initiatives across the Vertex portfolio to advance customer interactions across the mega accounts and where applicable, broad, timely and sustainable access (including solution development, implementation, pull-through and measurement) alongside cross-functional leaders
  • In tandem with HEOR, define strategic payer collaborations (i.e. health equity, quality, population health, etc.) with mega accounts (non-branded) across the various therapeutic categories
  • Partner with the Access COE (data, analytics and insights) and CRM teams responsible for customer and data insight tracking across the broad and evolving access environment and Vertex portfolio
  • Evaluate alternative contracting frameworks such as VBC/OBA/Warranties that support the clinical profile of the product and allow for easy measurement of a desire outcome
  • Deliver impactful insights and analysis to shape GTM strategies
  • Own and manage market access assessments/environmental scans to inform LRP assumptions including the development of action plans to manage risks and opportunities
  • Provide an annual landscape assessment across all access channels to support brand planning and upcoming launches (Channels: Payers/Mega Accounts, IDNs, GPOs, SP/SDs, Pharmacy) as well as to establish prioritization of products across access channels
  • Partner with external agencies and vendors as needed and ensure approvals and budget allocation as required.
  • Establish a value framework and communication platform to deliver a portfolio of PVPs via HEOR integration leveraging IT capabilities; uniform look and feel and construct (PIE, PVP, etc..) to maximize customer engagements

Knowledge and Skills:

  • Expert knowledge of US healthcare system, including gov't & commercial payers, hospitals, IDNs, policy, and the regulatory environment as well as the flow of funds
  • Previous strategic leadership experience in the pharmaceutical/biotech or healthcare industry; mega account experience
  • Understanding of alternative Value Base Contracts and evaluate various models and drive initiative and strategies to support OBA, warranty like models.
  • Proven track record of meeting or exceeding objectives & goals, both as an individual and as part of a team
  • Excellent communication skills with experience presenting to customers and internal leadership
  • Demonstrated ability to successfully navigate cross-functional teams, influencing without direct authority, with the interpersonal skills to foster collaboration and succeed in a highly matrixed environment
  • Ability to perform in a fast-paced environment, manage multiple priorities simultaneously, and work effectively across cross-functional teams

Education and Experience:

  • Bachelor's degree in relevant field, Master's Degree preferred
  • Deep market access experience (10 yrs) across all channels including experience in: payer marketing, contracting, Account Management (Payer)
  • Typically requires 10-12 years of MA experience or the equivalent combination of education and experience

Location: Remote, HQ or hybrid schedule (3 days a week in HQ)

Pay Range:

$201,200 - $301,800

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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