Project Scientist - Molecular and Medical Pharmacology

The Department of Molecular and Medical Pharmacology, David Geffen School for Medicine at UCLA is recruiting for an Assistant Project Scientist.

This position will contribute to collaborative research on organoid models, vascular-immune interactions, and tissue regeneration. Research will focus on the intestine and pancreas, including mechanisms of intestinal homeostasis and inflammation, vascular support of epithelial regeneration, and engineered endothelial platforms to improve organoid function. The position will employ cellular and molecular approaches, stem-cell-derived models, gene editing, and disease-relevant experimental systems to investigate vascular regulation of tissue repair and therapeutic regeneration.

Responsibilities include collaborating with the Principal Investigator in designing and executing research projects investigating organ-specific endothelial identity and vascular niches in intestinal and pancreatic tissues. The appointee will characterize vascular-immune interactions in inflammation and tissue injury; and develop or evaluate engineered host-immune cell coculture platform to support organoid function. The appointee will plan and perform experiments, optimize methods, collect and analyze data, maintain rigorous research documentation, and present results at laboratory meetings and scientific conferences. Additional responsibilities include assisting with grant-related research activities, preparing figures and manuscripts for publication, collaborating with investigators across disciplines, and providing scientific guidance to trainees as appropriate under the Principal Investigator's direction.

Ph.D. in cell biology, molecular biology, regenerative medicine, bioengineering, or a closely related field is required.

Experience with molecular and cellular assays, experimental design, quantitative data analysis, and scientific manuscript preparation is expected.

Demonstrated research experience in endothelial biology, intestinal or pancreatic biology, stem-cell or organoid models, inflammation, or tissue regeneration is highly desirable.

Experience in CRISPR/Cas9 gene editing, vascular-immune interactions, and preclinical models of intestinal disease or islet transplantation is preferred.

• 3 required (contact information only)

Applicants must provide the names and contact information of their references.

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

• "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.
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